Brillouin Microscopy and Raman Spectroscopy: Emerging Techniques for Improved Biomedical and Clinical Research

This exclusive double feature webinar is for those interested in finding out how Brillouin microscopy and Raman spectroscopy techniques can revolutionise your biophysical and biochemical analyses for life sciences, biomedical, and clinical diagnostic applications.

Brillouin Microscopy in Biomedical and Life Sciences

Brillouin light scattering (BLS) is a powerful technique that is used to determine sample properties from the spectral analysis of laser light scattered off thermally driven acoustic waves or phonons. In this presentation, Dr. Francesca Palombo reviews the recent advances in BLS microscopy for use in biophysical studies and outlines the challenges and opportunities presented. In particular we look at the interpretation and uniqueness of the optical signals obtained from acoustic phonons at gigahertz frequency.

Key learning objectives:

• Understand the basics of Brillouin light scattering
• Explore the hurdles in technical implementation
• Enable collaborative efforts to further advance instrument development and biomedical applications

Clinical Raman Spectroscopy: A potential panacea or just a complement to current clinical diagnostics?

Raman spectroscopy can provide a rapid, reproducible, and non-destructive pathological measure of disease and shows promise as a prognostic indicator of likely patient outcomes in a number of conditions. Raman spectroscopic tools can be utilized in the pathology lab to analyze cells, tissues, and fluids, applied at the point of care to provide real-time intraoperative information. Finally, it can be applied to open surgical fields with help from smart Raman needles or deep Raman approaches.

Whilst Raman spectroscopy shows great promise in the clinical diagnostics field, it is still unclear whether Raman will become the new gold standard for diagnosis or remain a complementary technique for difficult cases. In this presentation, Prof. Nick Stone will share recent work in translating Raman to the clinic and discuss its utility as a clinical tool.

Key learning objectives:

• Understand the principles of biomedical Raman spectroscopy
• Explore methods of deep Raman sampling in tissues (needle probes and spatially offset Raman)
• Hear clinical perspectives for novel Raman approaches.