In Vivo Bioluminescence
During bioluminescence light is emitted directly from the specimen without the need for excitation light. With no autofluorescence or scattering this allows for a high signal to background ratio. A further benefit for in vivo studies is that photobleaching and phototoxic effects can be minimized permitting study over extended duration.
Since the signals of bioluminescence are so weak it is essential that the detector has exceptionally low dark current. This is possible with the iKon CCD cameras via exclusive vacuum technology that provides the deepest possible cooling. When coupled with optimal photon collection efficiency from large pixels with >90% QE, the iKon CCD cameras allow detection of subtle yet important information from the specimen that would be missed using less optimal CCD cameras.
The iKon-M model has a 1 Megapixel sensor with 19 mm diagonal suited to C-mount lens. For those needing a wider field of view the larger iKon-L uses a 4.2 Megapixel format with F-mount fitment that allows a 39 mm diagonal field of view. Both models feature integrated shutters to avoid signal smear during readout. Extension tubes are available to adjust the focal distance. Extended response into the NIR is also possible allowing multi-reporter systems and improved sensitivity in deeper.