Oxford Instruments joins Chicago Quantum Exchange (CQE)
Oxford Instruments has announced today that they are partnering with the…
Marana is Andor’s high performance sCMOS camera platform for Astronomy and Physical Sciences, featuring 95% Quantum Efficiency (QE) and market-leading vacuum cooling to -45 °C. The platform offers solutions for large field of view and high-speed imaging/spectroscopy.
95% QE & -45 °C cooling - most sensitive back-illuminated sCMOS available
4.2 Megapixel / up to 32mm sensor – perfect for astronomy
Up to 74 fps full frame (faster with ROI) – track fast events without smear
> 99.7% linearity – superb quantitative accuracy across full dynamic range
Vacuum longevity & quality – no moisture on sensor, no QE decay
Marana is Andor’s latest high performance sCMOS camera platform, ideal for diverse applications within the physical sciences such as astronomy, Bose Einstein Condensation, quantum optics, hyperspectral imaging, neutron tomography and fast spectroscopy. Both Marana models feature 4.2 Megapixel sensors, 95% Quantum Efficiency (QE) and market-leading vacuum cooling to -45 °C, making Marana the most sensitive back-illuminated sCMOS platform available. Andor’s unique capability to deliver the ultimate in sCMOS sensitivity means Signal to Noise can be optimized under light starved conditions, ideal for tracking smaller orbital objects, spectroscopic detection of trace concentrations and BEC fluorescence detection of discrete numbers of atoms/ions. Higher sensitivity also means that exposure times can be shortened, facilitating faster frame rate measurements of dynamic processes.
Crucially, Marana sCMOS reads out 4.2 Megapixel high resolution arrays in less than 50 milliseconds, while maintaining very low read noise; hundreds of times faster than a similar resolution CCD detector.
The innovative ‘dual-amplifier’ approach to extended dynamic range is ideal for accurately visualizing and quantifying challenging scenes that have both extremely weak and bright regions, such as solar measurements and spectroscopic materials characterisations. Furthermore, to achieve best-in-class quantification accuracy, Andor have implemented enhanced on-head intelligence to deliver market-leading linearity of > 99.7% across the whole dynamic range, ideal for accurate photometry.
Marana 4.2B-11: This large field of view option utilizes a unique Anti-Glow Technology approach that enables one to usefully access the entire 2048 x 2048 array, offering an impressive 32mm sensor diagonal, which in combination with fast frame rates up to 24 fps (16-bit) and 48 fps (12-bit), renders the camera ideal for large sky scanning astronomy applications such as orbital debris tracking and Near Earth Asteroid detection. It is also ideal for dense multi-fiber hyperspectral applications. Marana 4.2B-11 also comes with a choice of QE profiles, the UV enhanced option (‘BU’) extending usefulness towards specific application requirements between 260nm and 400nm.
NEW Marana 4.2B-6: This high speed model achieves 74 fps (16-bit) and is the most sensitive back-illuminated camera available for imaging or spectroscopic applications requiring fast frame rates, such as Quantum Gas dynamics, fast high resolution spectroscopy, hyperspectral imaging and non-destructive imaging of sample dynamics via X-Ray or Neutron Radiography. The smaller 6.5 μm pixel is better suited to resolution matching across many laboratory-based optical imaging configurations, as well as in echelle spectroscopy.
The Marana platform can be readily adapted to Adaptive Optics wavefront sensing. Not only is it capable of producing hundreds of fps with ROIs, it is also specifically architected to minimize data transfer lag. Furthermore, the fast frame rate of Marana can be harnessed to massively extend dynamic range and effective well depth through fast stacking (accumulation) of images or spectra.
|All Marana Models|
|Up to 95% QE & lowest noise||Maximum signal to noise for light starved measurements. Detect smaller orbital debris; BEC fluorescence.|
|Vacuum cooled to -45°C||Very weak signals require lowest noise floor and longer exposures: Don’t be restricted by camera thermal noise!|
|4.2 Megapixel||High pixel resolution, maintaining image clarity over an extended field of view|
|The ONLY vacuum back-illuminated sCMOS||Andor’s proprietary UltraVac™ technology protects the sensor from (a) QE degradation, and (b) moisture condensation|
|Extended Dynamic Range (EDR) Mode||‘One snap quantification’ across the full dynamic range - perfect for Photometry.|
|> 99.7% linearity||Market leading quantitative accuracy over the whole signal range.|
|Fan and liquid cooling as standard||Liquid cooling for maximum sensitivity.|
|Adaptive Optics Ready||Minimize lag after data collection - transfer of row data immediately after exposing.|
|Marana 4.2B-11 (11 μm pixels)|
|Anti-Glow Technology||Suppresses the effects of sensor amplifier glow, allowing access to the full 4.2 Megapixel array.|
|11 μm pixels and 32 mm sensor diagonal||Largest field of view sCMOS, compatible with wide range of acquisition times. Large sky scanning;Tomography.|
|UV-Sensitive||High QE between 200 – 400nm. Ideal for UV wafer inspection.|
|NEW Marana 4.2B-6 (6.5 μm pixels)|
|6.5 μm pixels||Smaller pixels better suited to some optical systems, e.g. echelle astrospectroscopy and cold atom imaging.|
|USB 3.0 and CoaXPress connectivity options||USB 3.0 provides flexibility. CoaXPress enables the highest speeds to capture the most dynamic events|
|Low Noise Mode||Further reduces read noise floor at expense of pixel well depth, while maintaining a fast frame rate. Ideal when highest possible sensitivity is a priority.|
|High Speed Mode||Acquire images at high speeds of up to 74 fps in full frame 16-bit mode via CoaXPress! Boost speeds even further using regions of interest.|
|Superfast Spectroscopy Ready||On-head vertical pixel binning, ideal for dynamic spectroscopy (up to >25,000 spectra/sec).|
|Model||Marana 4.2B-11||NEW Marana 4.2B-6|
|Sensor Type||Back-Illuminated Scientific CMOS|
|Array Size||2048 (W) x 2048 (H) 4.2 Megapixel|
|Pixel Size||11 x 11 μm||6.5 x 6.5 μm|
|Image Area||22.5 mm x 22.5 mm (31.9 mm diagonal)||13.3 mm x 13.3 mm (18.8 mm diagonal)|
|Readout Modes||Rolling Shutter|
|Pixel readout rate||100 MHz (High Dynamic Range mode, 16-bit)
200 MHz (Fast Speed mode, 12-bit)
|310 MHz (Fast High Dynamic Range mode, 16-bit)
180 MHz (Low Noise mode, 12-bit)
|Quantum Efficiency||up to 95%|
|Read Noise (e-) median||1.6 e- (at any readout rate)||1.6 e- (Fast High Dynamic Range mode, 16-bit)
1.2 e- (Low Noise mode, 12-bit)
Air cooled (@-25°C )
Water/liquid cooled (@ -45°C)
| 0.7 e-/pixel/s
| 0.15 e-/pixel/s
|Photon Response Non-Uniformity (PRNU)||< 0.5% (@ half-light range)|
|Data range||16-bit (High Dynamic Range mode)
12-bit (Fast Speed mode)
|16-bit (Fast High Dynamic Range mode)
12-bit (Low Noise mode)
|Interface||USB 3.0||USB 3.0 and CoaXPress|
The Most Sensitive Back-illuminated sCMOS Available
Marana back-illuminated sCMOS cameras feature 95% Quantum Efficiency (QE) and market-leading vacuum cooling to -45 °C, minimizing noise floor. Benefiting from a unique vacuum design, Marana thermoelectrically cools to -25 °C using only the internal fan for heat dissipation, pushing down to a hugely competitive -45 °C utilizing liquid assisted cooling. The darkcurrent of the GS400BSI and GS2020BSI sensors are significant contributors to overall system noise, so effective cooling becomes essential. With air cooling, Marana has almost 5x lower darkcurrent than the nearest physical science competing camera.
Having the most sensitive Back-illuminated sCMOS camera carries a host of practical advantages within Astronomy and Physical Sciences, for example:
Anti-Glow: Accessing the Entire Sensor Array
The GSense400 back-illuminated sensor from GPixel, present in the Marana 4.2B-11 model and some competing cameras, is widely recognised to suffer from glow at the edges of the sensor. This glow manifests as false signal and is exposure dependent. The competitor approach is either to (a) live with the glow; (b) only use the middle region of the sensor; or (c) firmware restrict exposure times to 30 milliseconds in order to contain the impact of glow on experiments! Either way, this fundamentally restricts performance and usefulness across a range of applications, either through field of view limitation or through sensitivity limitation.
Andor have studied and characterised this sensor issue in detail and have developed and implemented an ‘anti-glow’ technology to suppress the effect of sensor glow on the image. The figure below shows a dark image of the GSense400BSI back-illuminated sensor with and without anti-glow technology – the difference it makes is stark and has enabled Andor to open up the full 2048 x 2048 array, while also allowing users to access exposure times up to several seconds.
Extended Dynamic Range and Superb Linearity
The innovative Dual Amplifier architecture of sCMOS sensors uniquely circumvents the need to choose between high or low gain amplifiers, in that signal can be sampled simultaneously by both high gain (low noise) and low gain (high capacity) amplifiers. As such, the lowest noise of the sensor can be harnessed alongside the maximum well depth, affording widest possible dynamic range. Uniquely for such a relatively small pixel design, this allows for dynamic range performance of 53,000:1 in Marana 4.2B-11.
Furthermore, on-camera intelligence delivers a significant linearity advantage, providing unparalleled quantitative measurement accuracy across the full dynamic range.
The fast, low noise readout of Marana sCMOS is also ideal for massively extending dynamic range through rapid stacking (accumulation) of multiple frames. For example, the plot below shows Dynamic Range and Effective Well Depth as a function of the number of stacked (accumulated) frames, plotted for Marana 4.2B-6. A Dynamic Range of 188,280:1, and a corresponding Effective Well Depth of 1,650,000 electrons can be reached with only 30 stacked frames. At maximum frame rate, this number of accumulated frames takes only 0.4 secs to acquire, achieving > 2 fps. This capability is significant for a range of challenges across imaging and spectroscopic characterisations.
Fast Frame Rates
The sCMOS sensors in Marana 4.2B-6 and Marana 4.2B-11 have highly parallel readout architecture, facilitating high data readout rates and therefore fast frame rates. All columns possess their own Amplifier and Analogue to Digital Converter (ADC), meaning that all columns are read out in parallel. Region of Interest (ROI) can be utilized to considerably boost frame rates further.
Marana 4.2-6 offers particularly fast frame rate capability of 74 fps (full array) while maintaining full 16-bit data range, rendering it ideal for dynamic applications while avoiding motion smear, such as Quantum Gas (e.g. BEC) dynamics or Hyperspectral Imaging.
Marana 4.2-11 combines rapid frame rates with extended field of view, ideal for applications ion astronomy such as Space Debris and NEO tracking, Pulsar imaging, Solar polarimetry and Lucky imaging/Speckle Interferometry.
Marana 4.2B-11 is architected to offer both 16-bit and 12-bit modes. 12-bit is selected specifically to accelerate frame rate by 2x, while sacrificing wide dynamic range, useful for imaging fast phenomena that are exclusively low light, such as following BEC dynamics on discrete numbers of fluorescent cold atoms.
|Max Frame Rate (fps)||Marana 4.2B|
|ROI Size (W x H))||16-bit||12-bit|
|2048 x 2048||24||48|
|1608 x 1608||30||61|
|1410 x 1410||35||69|
|1200 x 1200||41||81|
|1024 x 1024||48||95|
|512 x 512||95||190|
|256 x 256||190||378|
|128 x 128||378||750|
|2048 x 8||5415||9747|
|1200 x 8||5415||9747|
Rolling Shutter and Simulated Global Shutter
Both Marana models utilize a Rolling Shutter exposure mechanism. Rolling shutter essentially means that different lines of the array are exposed at different times as the read out ‘wave’ sweeps through the sensor, a row at the bottom starting the exposure approximately 21 ms before rows at the sensor’s distal edge. The lowest readout noise and fastest frame rates are available from this mode. Rolling shutter only presents an issue when imaging relatively large, fast moving objects within the field. Then, aside from the risk of motion blur that can affect any imaging condition in which rate of motion is being temporally under-sampled, there is an additional possibility of rolling shutter spatial distortion. However, distortion is less likely when relatively small objects are moving at a rate that is being temporally oversampled by the frame rate, which in fact describes the vast majority of use cases.
A further potential downside of rolling shutter is that different regions of the exposed image will not be precisely correlated in time to other regions, which can be essential for some applications. For example, if a cell is electrically stimulated and it is important to measure the onset of calcium sparks relative to the stimulation event, then rolling shutter should not be used. In this case, a true global shutter mode is required, available in Zyla 5.5 and Neo 5.5 sCMOS cameras.
Multiple Optical Mount Options
Marana 4.2B-11 ships as default with standard F-mount optical coupling, however, the user can readily convert the camera for use with a C-mount lenses, simply by selecting this additional optical mount accessory at time of order. C-mount may be used with cropped sub-array sizes up to 1400 x 1400, yielding a 22mm sensor diagonal.
For attachment to various professional telescope configurations, the Marana 4.2B-11 front end can be direct mounted, providing f/# 0.7 with 72° cone angle. Through engagement with Andor’s Customer Special Request (CSR) service, custom mount faceplates can be tailored to your specific optical needs.
Likewise, while the smaller field of view Marana 4.2B-6 ships as native C-mount, an F-mount accessory may be ordered to convert the camera for use with F-mount lenses, for example to access lower f# input.
Fast Spectroscopy Mode
Marana 4.2B-6 and Marana 4.2B-11 can be readily adapted to the needs of fast spectroscopy, yielding up to greater than 25K spectra/sec. Such spectral rates are ideal for following fast reaction dynamics on sub-millisecond stopped flow timescales. Fast spectral kinetics capability can also be used for ‘pseudo-gated’ time-resolved functionality, whereby the first series of spectra from a fast series can be discarded to ‘gate out’ the effects of the initial exciting laser pulse.
On-camera FPGA real time asymmetric pixel binning allows for optimized optical matching and maximum photon collection, while a complimentary on-camera bit depth of 32-bit capability allows for very high binned effective well depths, ideal for fast transient absorption measurements.
Spurious Noise Filter
Andor’s Marana sCMOS camera comes equipped with an in-built FPGA filter that operates in real time to reduce the frequency of occurrence of high noise pixels. This real time filter corrects for pixels that would otherwise appear as spurious ‘salt and pepper’ noise spikes in the image.
The appearance of such noisy pixels is analogous to the situation of Clock Induced Charge (CIC) noise spikes in EMCCD cameras, in that it is due to the fact that we have significantly reduced the noise in the bulk of the sensor that the remaining small percentage of spuriously high noise pixels can become an aesthetic issue. The filter employed dynamically identifies such high noise pixels and replaces them with the mean value of the neighbouring pixels.
The Marana platform can generate a timestamp for each image that is accurate to 25 nanoseconds. Accurate timestamps can be important where precise knowledge of frame time impacts temporal dynamic analysis. This is especially important for fast events, where computer and interface latencies need to be considered, for example in Pulsar studies.
Flexible pixel binning
The Marana models feature on-camera flexible pixel binning, user definable to 1 pixel granularity. Greater binning flexibility can be useful for some photon starved applications where resolution can be sacrificed in favour of enhanced photon collection area per pixel - e.g. extremely low light luminescence experiments.
The Andor GPU Express library has been created to simplify and optimize data transfers from camera to a CUDA-enabled NVidia Graphical Processing Unit (GPU) card to facilitate accelerated GPU processing as part of the acquisition pipeline. GPU Express integrates easily with SDK3 for Andor sCMOS cameras, providing a user-friendly but powerful solution for management of high bandwidth data flow challenges; ideal for data intensive applications such as Light Sheet Microscopy, Super-Resolution Microscopy and Adaptive Optics.
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