Part of the Oxford Instruments Group

ZL41 Cell sCMOS

ZL41 Cell is the next generation in the highly successful Zyla sCMOS series! We have carefully refined and perfected the design. Truly exceptional imaging flexibility, value and compatibility. Specifically for life science imaging.

  • Sharp: ~100 nm resolution

  • Fast: up to 100 fps

  • Sensitive: up to 82% QE

  • Accurate: >99.8% linearity

  • Flexible: 4.2 and 5.5 Megapixels

  • Productive: up to 22 mm field of view

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The ZL41 Cell takes all the strengths of the highly popular Zyla series into a new edition specifically for life science researchers!​

  • ZL41 Cell 4.2 supercedes the Zyla 4.2 PLUS. Delivering up to 82% QEmax, coupled with sub-electron read noise. The broad QE profile provides excellent coverage of the visible/NIR wavelength range, highly optimized to a wide range of common fluorophores. The high sensitivity permits use of shorter exposure times, faster frame rates and reduced phototoxicity.​
  • ZL41 Cell 5.5 replaces the Zyla 5.5 and remains the ideal cost-effective upgrade solution for a microscope. It offers a 22 mm format sensor with 64 % QE. Uniquely, it offers a Global Shutter mode that is ideal for snapshot imaging of fast-moving objects without temporal distortion.​

The ZL41 Cell 4.2 is ideal for applications that benefit from optimal sensitivity and speed, such as calcium imaging, light sheet microscopy and super-resolution microscopy. Packed with features such as:​

  • SRRF-Stream+: (ZL41 Cell 4.2). Make your standard fluorescence microscope capable of Super-Resolution. Our cost-effective and easy to use real time super-resolution is available on ZL41 Cell 4.2 models. Use normal labelling and find out how your imaging can be taken to the next level.​
  • LightScan PLUS: (ZL41 Cell 4.2) features FlexiScan & CycleMax functionality, permitting simple and flexible adaption of the Rolling Shutter scan mode to applications such as Scanning LightSheet Microscopy and Line Scan Confocal.​
  • FCS Mode: Obtain the fastest speeds from minimal height ROIs configured for Fluorescence Correlation Spectroscopy experiments. ZL41 Cell 4.2 outputs a sustained 26,041 fps (2048 (w) x 8 (h) ROI) for exceptional temporal resolution.​
  • GPU Express Simplify and optimize data transfer from the camera – ideal for today’s data intensive imaging experiments. Leverage CUDA-enabled NVidia GPU processing to accelerate the data acquisition pipeline with GPU Express.​

Superior data transfer efficiency and 12-bit high speed mode combine to deliver an incredible 53 fps through the super-convenient USB 3.0 interface, with industry fastest Region of Interest (ROI) frame rates. With this capability, speed is on tap to allow users to follow faster dynamic processes with improved temporal resolution. Opt for the Camera Link version to access up to a blistering 100 fps (full resolution).​

  • ZL41 Cell also offers industry-leading linearity (99.8%) for unparalleled quantitative accuracy of measurement across the full dynamic range.​
  • An all new sensor chamber design provides even greater robustness and longevity (3-year chamber integrity warranty).​
  • ZL41 Cell models share software compatibility with the previous editions of Zyla 4.2P and 5.5 models​

Up to 82% QE - Highest and broadest available sCMOS QE. Optimized to a wide range of common fluorophores. Enables shorter exposures, faster frame rates and reduced photobleaching.

0.9 e- read noise - Lowest read noise sCMOS. Significantly lower than any CCD.

Industry Fastest Frame Rates - Follow faster processes. Industry-fastest USB 3.0 frame rates, 53 fps (full frame). 100 fps (full frame) sustained via Camera Link.

4.2 and 5.5 megapixel sensor formats and 6.5 µm pixels - Delivers extremely sharp resolution for modern microscopes with C-mount ports.

SRRF-Stream+ - Super Resolution made cost effective, flexible and easy. New ZL41 Cell 4.2 compatible with our real-time Super-resolution Technology.

LightScan PLUS - Reduce background and improve contrast and resolution in scattering samples. Designed to allow users to optimise signal strength and confocality concurrently in applications such as Scanned Light Sheet Microscopy and Line Scanning Confocal Microscopy.

FCS Mode - Obtain the fastest speeds from minimal height ROIs configured for Fluorescence Correlation Spectroscopy experiments

GPU Express - Simplify and optimize data transfers from camera to a CUDA-enabled NVidia Graphical Processing Unit (GPU) card to facilitate accelerated GPU processing as part of the acquisition pipeline

Compatible - Maintains compatibility with previous Zyla series with no changes at EEPROM level.

Robust - New mechanical design for greater longevity and sensor protection. 3 years warranty on sensor chamber integrity.

Ultra - Low Fan Vibration - Designed with vibration sensitive experiments in mind, such as super-resolution microscopy.

Dual-Gain Amplifiers - Maximum well depth and lowest noise simultaneously, affording extended dynamic range of 33,000:1

12-bit and 16-bit modes - 12-bit for absolute fastest frame rates through USB 3.0; 16-bit for full dynamic range.

Extensive FPGA on-head data processing - Essential to ensure best image quality and quantitative fidelity from sCMOS technology.

Hardware Timestamp - FPGA generated timestamp with 25ns accuracy.

Dynamic Baseline Clamp - Essential to ensure quantitative accuracy across the image area and between successive images of a kinetic series.

Python Ready - Take control with our new python integrated SDK. Ideal for custom system integrations.

Water Cooled Option - Option for vibration sensitive applications. Available under request

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