Since its launch, more than 200 papers have been published in high profile journals using Dragonfly. Dragonfly is a unique spinning disk confocal system that revolutionised the way imaging systems are perceived.
Before Dragonfly, there was no instrument compatible with live-cell imaging that could deliver deep-tissue imaging, as well as single-molecule localisation microscopy.
At Andor it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research. We were born out of Queen’s University and have never forgotten our roots. It excites us that the Dragonfly platform is being widely used in papers published in high-impact journals like Nature, Neuron, Journal of Cell Biology and more.
64% of Dragonfly papers are published in journals with an impact factor of > 5
Dragonfly is much more than a high-speed confocal. TIRF, SRRF, and powerful laser-based widefield illumination can deliver super-resolved understanding of processes and place them in the context of whole tissues and organisms. Combined with Imaris, market leading 3D analysis software, our workflows address a broad range of disciplines with a single solution.
Clinical & Drug Studies
Centrosomes & Cilia
|The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis||Nature Cell Biology|
|Long-Term Potentiation Requires a Rapid Burst of Dendritic Mitochondrial Fission during Induction||Neuron|
|Melatonin promotes human oocyte maturation and early embryo development by enhancing clathrin‐mediated endocytosis||J Pineal Res.|
|A jumbo phage that forms a nucleus-like structure evades CRISPR–Cas DNA targeting but is vulnerable to type III RNA-based immunity||Nature Microbiology|
|Multiplexed 3D super-resolution imaging of whole cells using spinning disk confocal microscopy and DNA-PAINT||Nature Communications|
|Building sensory axons: Delivery and distribution of NaV1.7 channels and effects of inflammatory mediators||Science Advances|
|TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts||Nature Communications|
|MRE11 UFMylation promotes ATM activation||Nucleic Acids Research|
|PDZD8 mediates a Rab7-dependent interaction of the ER with late endosomes and lysosomes||PNAS|
|INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division||Journal Cell Biology|
|A Contraction Stress Model of Hypertrophic Cardiomyopathy due to Sarcomere Mutations||Stem Cell Reports|
|Glia Promote Synaptogenesis through an IQGAP PES-7 in C. elegans||Cell Reports|
|Nephron progenitor commitment is a stochastic process influenced by cell migration||elife|
|A nuclear role for the DEAD-box protein Dbp5 in tRNA export||elife|
|Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates||elife|
|SRRF-stream imaging of optogenetically controlled furrow formation shows localized and coordinated endocytosis and exocytosis mediating membrane remodeling||ACS Synth. Biol|
|In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism||Frontiers in Cell and Developmental Biology|
|Two distinct actin filament populations have effects on mitochondria, with differences in stimuli and assembly factors||Journal Cell Science|
|Applications of Nanocellulose/Nanocarbon Composites: Focus on Biotechnology and Medicine||Nanomaterials|
|Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling||Scientific Reports|
We presented actual membrane trafficking events captured using Andor’s Super-Resolution Radial Fluctuation (SRRF-Stream) implemented via the highly sensitive iXon camera. Andor´s imaging technology offered new insights on the role of PI3-kinase in clathrin-mediated pinocytosis. Understanding this fundamental mechanism of vesicle trafficking could have implications for many diseases.
Cytokinesis is the physical separation of two cells that occurs after the completion of mitosis. In this webinar, we will present how we used a combination of optical techniques such as subcellular optogenetics, FRAP, TIRF, confocal imaging (Dragonfly) and SRRF-stream imaging to uncover the membrane dynamics during the final steps of cytokinesis.
At the recent 3rd birthday celebration of the Andor Dragonfly confocal system, Dr. Peter March (Bioimaging Facility at The University of Manchester), Biology's answer to Professor Brian Cox, took us on a humorous journey through the life of a Senior Experimental Officer at a growing Bioimaging Facility, including a brief history of Microscopes from the 17th century!
The Andor Learning Center hosts a wide range of tutorial videos, technical articles and webinars to guide you through the range of products for all your imaging needs. We have provided some links below which will get you started on some of our most recent uploads.
Dragonfly is an invaluable system for us and the busiest in our core facility. It’s been very helpful for our model organisms and organoid work, as well as being the first system in ESRIC which can do live super-resolution imaging.
Dragonfly integrates speed of acquisition coupled with little or no photobleaching which has helped me immensely during my mitochondrial imaging. It is a wonderful system to perform both live and fixed cell imaging.