Mosaic 3 is a patented instrument platform built around a MEMS Digital Mirror Device (DMD). The DMD comprises an array of individually controllable micro-mirrors that can be switched “on and off”. DMD arrays contain hundreds of thousands to millions of micro-mirrors allowing precise control of illumination in user defined patterns or across multiple regions. These properties have made mosaic an exceptionally useful and versatile tool for optogenetic and photostimulation experiments.
Features and Benefits of Mosaic 3
FRAP is the basis for many experiments that seek to determine processes that may be hidden by background fluorescence levels such as protein turnover, diffusion rates and many more.
Mosaic 3 is ideal for experiments that require biomolecules to be uncaged and photoactivated into their active state.
Photoactivation can be used in many ways: study cell dynamics & signalling, intracellular organelle tracking, or for ion imaging or neurotransmission.
Mosaic 3 allows you to continuously illuminate an arbitrary mask in the imaging field. You simply can’t do this using laser-scanning microscopes, which never provide true simultaneous illumination. This important feature combined with ease of use and direct interfacing with software makes the Mosaic a unique and valuable tool for the optogenetic community.
Professor Harald Janovjak, Matthew Flinders Professor in Molecular Medical Bioengineering and Head of the Synthetic Physiology Laboratory at Flinders University