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High Power Laser Engine

Andor's high-end laser engine delivers high power for SMLM applications and photostimulation imaging with mosaic and micropoint. Further, the user can perform gentle live imaging for days using the neutral density filters.

  • Two to seven multimode laser lines in a single chassis and up to ten lines in dual configuration

  • Wide VIS-NIR wavelength range

  • Power range 400 to 2500 mW

  • Two or three fast galvo-switched fibre outputs

  • Suitable for dSTORM, PAINT single molecule applications and photostimulation


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HLE offers two to seven multimode laser lines in a single chassis and up to ten lines in dual configuration. Both engines can be outfitted with two or three fast galvo-switched fibre outputs.

The new HLE benefits from lower coherence multimode lasers and with power levels ranging from 400 to 2500 mW is suitable for studies like dSTORM and PAINT (point accumulation in nanoscale topography) single molecule applications and photostimulation. HLE is equipped with direct modulation (2-100%) as well as serial neutral density filters enabling a further 1,2 or 3 optical density units for ultra-low light live-cell imaging. Active power and thermal management deliver long-term, ultra-stable, agile illumination.

Wide VIS-NIR spectral range - The HLE is compatible with a wide range of laser sources and wavelengths; the current selection covers from 405 up to 780 nm​

Direct modulation Lasers - Obtain exceptional spectral range, high efficiency and stability​

Three-port switch: multi-function flexibility - Switch effortlessly between modes​

Multi-line laser source - Flexible configuration allows up to 7 lines in the HLE-700 and up to 10 lines in dual configuration

Thermally managed - Effective thermal regulation helps to provide long-term, ultra-stable performance

Borealis-compatible - Benefit from enhanced throughput and uniformity in widefield and spinning disk confocal systems

Related Applications

Fluorescence Microscopy

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