Making Sense of Sensitivity in sCMOS Cameras

In this webinar we will take a look at Andor’s latest back-illuminated sCMOS cameras the Sona. The latest model, the Sona 4.2B-6 has just recently been released. It features a back-illuminated 4.2 Megapixel sensor with 6.5 µm pixels. This format matches perfectly with modern microscope port sizes, providing optimal resolution for the widely used 40x and 60x magnifications. A QE of 95% maximizes signal collection, which when combined with thermoelectric cooling to -45°C, results in the lowest noise floor, to allow the highest possible sensitivity for demanding low-light applications. All Sona models feature an exclusive permanent vacuum seal to ensure optimum performance and longevity.

Some of the questions we will address include: How do these latest cameras compare with the previous generation of sCMOS cameras that became the dominant camera technology over the last 10 years? And what now for EMCCD cameras - are they still relevant for the most demanding applications such as single molecule studies?

Learning objectives:

• Back-illumination technology and how this and other factors affect camera sensitivity
• What camera specifications are important for fluorescence microscopy
• The strengths and weaknesses of the different camera technologies
• How to best match a camera to your application

At the end of this webinar our Product Specialist, Dr. Alan Mullan will also respond to questions.