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Dragonfly delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity.
Its unrivalled combination of speed and sensitivity allows researchers to discover unforeseen dynamic events and image live organisms for days. The new B-TIRF and super resolution modules reveal smaller details, such as the dynamics of viral infection and the ultrastructure of chromatin or organelles.
NEW: Flagship Confocal System: Dragonfly 600
Deeper Imaging. Deeper Insights. Deeper Understanding.
Dragonfly 600 spinning disk confocal delivers leading performance for both industrial and academic users. It integrates super-resolution solutions compatible with confocal, widefield or TIRF. Furthermore, it incorporates the newly developed High Power Laser Engine (HLE) and new TIRF imaging modality, which exploits Borealis® illumination, B-TIRF (Borealis TIRF) for easy setup, more even illumination and thus more usable data across the field of view.
Use the hotspots below to explore the key features and benefits of Dragonfly 600.
Whether imaging glial cells, axonal transport, large tissue sections, expanded samples (Expansion Microscopy), or super-resolved dendritic spines (SMLM), Dragonfly is the instrument of choice.
The high sensitivity, low phototoxicity/ photobleaching and speed are ideal features for live cell imaging applications such as microtubule dynamics or intracellular organelle trafficking
With B-TIRF researchers can address live events at the edge of the coverslip, such as vesicle fusion or membrane receptor trafficking. B-TIRF delivers increased signal to noise in SMLM applications
The HLE can be used in combination with any imaging modality (confocal, widefield and B-TIRF) for SMLM applications, such as ultrastructural organisation of organelles, chromatin and epigenetic organisation, mitochondrial membrane structure.
Dragonfly allows researchers to study cancer cell behaviour interaction with the environment and spatial distribution of the tumor both in fixed and live cells.
Dragonfly's optimized pinhole size allows imaging very deep into thick organisms - up to the millimetre range.
Omics research is used for multiple applications, such as predicting disease progression based on gene expression mappings, assessing tumor microenvironments and cancer severity, etc.
Omics-related sciences gather information about Xn biological molecules to characterize and quantify entire pools of molecules.
Dragonfly's highly sensitive detectors, exceptionally high background rejection, acquisition speed and Uniform illumination make it the perfect system for Omics applications
The resolution and sensitivity delivered by Dragonfly 600 makes it a unique system for studying micro-organisms:
Dragonfly performs at a very high level and its ease of use allows researchers to acquire valuable data at speed. The system really excels for applications that are more demanding, such as high resolution live cell imaging.
Derek Toomre, PhD - Professor of Cell Biology at Yale School of Medicine.
At its core, Dragonfly, is a multi-point confocal for high-speed and high-sensitivity imaging.
Borealis Total Internal Reflection Fluorescence (B-TIRF) is Andor’s proprietary TIRF module available on Dragonfly 600.
With Dragonfly you can select from a number of super-resolution approaches all from the same imaging system.
SRRF (Super-Resolution Radial Fluctuations) offers a highly effective software-based approach to super-resolution imaging. Our exclusive development, SRRF-Stream+, accelerates processing by delivering real-time super-resolution.
Laser-illuminated widefield fluorescence is ideal for studies that do not benefit from confocal imaging. Dragonfly users can easily change to widefield mode, with no need to switch microscope ports.
All imaging modalities can be combined with transmitted light techniques (DIC or phase contrast) to expand your imaging capabilities even further. DIC or Phase Contrast can be used in a variety of ways including:
Dragonfly is fast, sensitive, and fantastically flexible. We have 120 research groups working at our Core Facility every year, and they bring in everything you could imagine to image. Having the flexibility to switch between different modes and colors, and having a system that is very sensitive for single-molecule imaging through to spinning-disk confocal microscopy, is amazing for us.
Prof. Jeffrey Caplan - Director of Bioimaging and Associate Professor, University of Delaware.
Fusion has been designed to meet the requirements of today’s researchers providing ease of use and immediate visual feedback for data review.
We have worked with Picasso developers to allow Imaris .ims files o be read in Picasso. Users have the flexibility to go to open-source software to retrieve SMLM data and 3D SMLM localizations.
3D rendering and statistical measurements are then delivered in Imaris. Please read our article on the acquisition to analysis workflow.
Imaris Core is included in all Dragonfly models, allowing users to:
A flexible, multi-modal platform that offers confocal, laser based widefield, transmitted light and SRRF-Stream+ functionality in one system.
A complete system that builds on the capabilities of the 200 model to also include SMLM, 3D super-resolution module, B-TIRF and Zoom Illumination.