Over the past 10 years, a new fluorescence microscopy technique has come to the fore that is faster and less phototoxic than other microscopy techniques, making it ideal for studying living organisms and the biological processes that take place within them. Known as light-sheet microscopy (LSM) or selective plane illumination microscopy (SPIM), its key feature is that the illumination is done perpendicularly to the direction of observation.
We have recently published a Light Sheet Microscopy e-book which can be downloaded using the button below. This is free to download and covers the latest advances in light sheet microscopy, case studies and application notes from some of the leading researchers in the field.
Learn how our customers use Andor sCMOS cameras for their Light Sheet Applications. We have a range of case studies available to read which highlight different applications of light sheet microscopy with a variety of light sheet microscopy set-ups. The various light sheet setups range from four-lens SPIM to inverted SPIM to SiMView to name but a few.
"We've tested the new Andor Zyla 4.2, the camera sensitivity is impressive even at very small exposure times. Thanks to this we were able to achieve long time-lapse imaging without apparent bleaching."
Ricardo Henriques University College London
"Light sheet microscopy benefits directly from the latest camera technology. The new Andor Zyla delivers high speed, sensitivity and resolution in one package and unleashes the full potential of our microscopes."
Jan Huisken Max Planck Institute, Dresden
"The Andor Zyla 4.2 sCMOS camera provides an impressive combination of field-of-view, sensitivity, resolution, and speed. It is a highly versatile camera that can be used for many different applications."
Dr. Kurt Thorn UCSF
Application Videos and Webinars
Further reading material on Andor's innovations in Light Sheet Microscopy can be found below in a series of case studies, press releases and published papers.