Endothelial Cells

AFM and force spectroscopy for single cell and single molecule studies. (a) Height image of bovine capillary endothelial cells on gelatin substrate; (b) Deflection (feedback error) image of these cells show cytoskeletal detail; (c) Specific ligand-receptor rupture event (*) for streptavidin substrate and biotin-functionalized cantilever tip; (d) Aspecific binding for clean glass surface and biotin-functionalized cantilever tip. 1 µm scan. Images courtesy of A. Chandrasekaran and K.J. Van Vliet. K.J. Van Vliet et al. / Acta Materialia 51 (2003) 5881?5905.